برنامج تحليل الحمض النووي DNA والجينات Molecular Biology Insights Oligo v7.57

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    • Sep 2018
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    برنامج طبي نادر ومتخصص جدا لتحليل الحمض النووي الـ DNA و الجينات


    Molecular Biology Insights Oligo v7.57

    OLIGO Primer Analysis Software is the essential tool for designing and

    analyzing sequencing and PCR primers, synthetic genes, and various kinds of

    probes including siRNA and molecular beacons.

    Based on the most up-to date nearest neighbor thermodynamic data, Oligo's

    search algorithms find optimal primers for PCR, including TaqMan, highly

    multiplexed, consensus or degenerate primers. Multiple file batch

    processing is possible. It is also an invaluable tool for site directed


    For each primer or primer pair, Oligo's various analysis windows show a

    multitude of useful data, such as DNA and RNA secondary structure, dimer

    formation, false priming and homology, internal stability, composition and

    physical properties. With Oligo you can analyze open reading frames down to

    predicted molecular weight and pKa of proteins, and search for restriction

    enzyme sites, not only in DNA but also in reverse-translated proteins.

    The first version of the software appeared on the market in 1989. It went

    through several modifications, and the last one, the change from version 6

    to 7, was the most comprehensive. Oligo 7 can automatically select multiplex

    primers, process sequence files in batch modes, automatically design PCR

    primers to cover multiple DNA regions in just one search and automatically

    find primer/probe sets for real time PCR or finds nested primers sets. Oligo

    search protocols (scoring system) may be customized in detail, so you may

    optimize the results according to your specific needs.

    OLIGO's comprehensive functionality matches several other commercial primer design applications put together, so you can design probes for high throughput analysis, multiplex them or focus on one set of primers/probes and optimize it for a new, not yet published application.


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