أستغفر الله العظيم ... سبحان الله وبحمده



العودة   منتديات داماس > البوابه الهندسية > كتب هندسة مدني, معماري, ميكانيك وغيرهم > كتب الهندسة الطبية الحيوية والبيولوجية


مواضيع مميزة  


آخر عشرة مواضيع المواضيع النشطة


30-09-2014, 08:43 PM
سعد الدين متصل
المسؤول الفني
رقم العضوية: 3
تاريخ التسجيل: Mar 2003
الإقامة: Türkiye
المشاركات: 39,285
إعجاب: 8,752
تلقى 15,567 إعجاب على 5,204 مشاركة
تلقى دعوات الى: 4874 موضوع
    #1  

Oxidative Stress and Diseases


Oxidative Stress and Diseases

Oxidative Stress Diseases

Preface
The increased level of reactive oxygen species (ROS) in living organisms over 60 years ago was implicated in the development of diseases and aging (Harman, 1956; 1983). This book is a collective scientific monograph presenting several important aspects related to ROS role in human and animal pathologies. In 1985, German scientist Helmut Sies first denoted oxidative stress concept, which immediately attracted attention of researchers in diverse basic fields. Several discoveries substantially stimulated the interest to ROS as ones related to many diseases. They were descriptions of catalytic function of superoxide dismutase (erythrocuprein or hemocuprein) by McCord and Fridovich (1969) and role of superoxide anion in host defense against pathogens (Babior et al., 1973; McCord, 1974). The knowledge on ROS roles in diverse biological processes in living organisms was summarized in an excellent book by Halliwell and Gutteridge (1999). An obvious question arises during the accumulation of data on the ROS involvement in diseases: is oxidative stress their reason or consequence? In most cases, we cannot directly answer the question, but it is absolutely clear that reactive species accompany many pathologies. And even more – in some cases antioxidants were able to attenuate the symptoms, but in most cases the expectations on antioxidants as a panacea for many diseases was not confirmed what finally led to understanding that suppression of free radical processes also may have negative consequences for the organisms. In 1980, Arthur Hailey described the miracle drug saving many lives in a novel “Strong Medicine”. That was a rather efficient antioxidant, but side effects were related to suppression of immune system and weakening defense against infections, the effects well known now. More and more recent data reflect the situation that ROS are involved in many living processes, and organisms delicately control their levels. The question on low specificity of ROS effects has also been clarified to some extent. Really, being chemically highly reactive, the processes with ROS participation are determined first of all by their species and forms, temporary-spatial generation and elimination, presence of available sensors and targets. So we are really dealing with a complicated net that is an integral part of living organisms and is usually under strict control, but if not properly controlled may result in injuries of diverse nature. Our understanding of ROS role in biological systems has evolved from recognizing of them as clearly damaging side-products of cellular metabolism changing normal physiological processes, through appreciation of their roles as critically important elements of host defense against pathogens, to recognition of their role as regulators of many physiological processes.



On December 16, 2011, a Google Scholar search for “oxidative stress” and “disease” yielded about 1,430,000 publication hits, whereas in Scopus and Pubmed databases it yielded 135,381 and 94,195 hits, respectively. Enormous interest to the ROS roles has been indirectly confirmed by the project by InTech Publisher, with the book on oxidative stress. We initially planned to publish one book, but when the project was started, more than 90 propositions were received. Therefore, recognizing the popularity of the field and interest of many scientists to share their knowledge with a broad auditory, we decided to divide the propositions and publish three books.




The development of hypothesis of oxidative stress in the 1980s stimulated the interest of biological and biomedical sciences that extends to this day. The contributions in this book provide the reader with the knowledge accumulated to date on the involvement of reactive oxygen species in different pathologies in humans and animals. This book should appeal to many researchers, who should find its information useful for advancing their fields.







InTeO -- 2012 -- ISBN: 9535105527 9789535105527 -- 624 pages -- PDF -- 17 MB




Download


http://mediafire.com/download/02/003/BIODEVICES...lectronics.rar

Sponsors







المواضيع المشابهه
الموضوع كاتب الموضوع المنتدى مشاركات آخر مشاركة
Atlas of Ear Diseases of the Dog and Cat سعد الدين المحاضرات والكتب والبرامج الطبية 2 12-11-2014 08:31 PM
Soil Stress Strain Behavior سعد الدين كتب هندسة مدني, معماري, ميكانيك وغيرهم 1 11-07-2014 01:45 AM
امراض الغدد الصم ENDOCRINE DISEASES Jacky الطب البشري - العلاج بالأدوية و الأعشاب الطبية 34 05-05-2011 05:27 AM
Structural and stress analysis alanjalal كتب هندسة مدني, معماري, ميكانيك وغيرهم 1 23-02-2009 09:49 AM
Diseases and Disorders: The World's Best Anatomical Charts samirahmed برامج 0 22-04-2006 05:55 AM

01-10-2014, 11:31 PM
raedms غير متصل
VIP
رقم العضوية: 81535
تاريخ التسجيل: May 2007
المشاركات: 23,913
إعجاب: 618
تلقى 4,088 إعجاب على 721 مشاركة
تلقى دعوات الى: 1311 موضوع
    #4  
بارك الله فيك


سبحان الله وبحمده سبحان الله العظيم


13-07-2016, 06:11 AM
كمال بدر غير متصل
الوسـام الماسـي
رقم العضوية: 435810
تاريخ التسجيل: Nov 2013
الإقامة: جمهورية مصـر العربية
المشاركات: 21,040
إعجاب: 4,805
تلقى 5,316 إعجاب على 2,657 مشاركة
تلقى دعوات الى: 858 موضوع
    #6  

جزاكَ الله خيراً أخي الكريم عن هذا الطرح القيم والنافع والمفيد ... تقبل تحياتي.



سُبْحَانَ اللَّهِ وَبِحَمْدِهِ ،-، سُبْحَانَ اللَّه الْعَظِيم

موضوعات العبد الفقير إلى الله الغنى بالله المتوكل على الله.



 


Oxidative Stress and Diseases

English

Powered by vBulletin® Version
Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.
The owner and operator of the site is not responsible for the availability of, or any content provided.
Topics that are written in the site reflect the opinion of the author.
جميع ما يُطرح من مواضيع ومشاركات تعبر عن رأي كاتبها ولا تعبر عن رأي مالك الموقع أو الإدارة بأي حال من الأحوال.