أستغفر الله العظيم ... سبحان الله وبحمده



العودة   منتديات داماس > البوابه الهندسية > كتب هندسة مدني, معماري, ميكانيك وغيرهم > كتب الهندسة الطبية الحيوية والبيولوجية


مواضيع مميزة  


آخر عشرة مواضيع المواضيع النشطة


27-09-2014, 08:26 PM
سعد الدين متصل
المسؤول الفني
رقم العضوية: 3
تاريخ التسجيل: Mar 2003
الإقامة: Türkiye
المشاركات: 40,834
إعجاب: 9,070
تلقى 15,567 إعجاب على 5,204 مشاركة
تلقى دعوات الى: 5086 موضوع
    #1  

Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications


Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications

Chemistry Bioconjugates: Synthesis, Characterization, Biomedical

PREFACE
Combining characteristics of different components into one
to generate new molecular systems with unique properties by
simply linking one or more (macro)molecules is defined as
bioconjugation. The ability to create such biohybrids either
covalently or non-covalently has allowed major breakthrough
in many industrial and biomedical areas such as bioseparation,
targeting, detection, biosensing, biological assays,
etc. This book provides a comprehensive account on the
chemistries involved in the formation of bioconjugates, followed
by an extensive review of all the different types of
bioconjugates generated so far from polymers, dendrimers,
nanoparticles, carbon nanotubes, hydrogels and so on for
different bio-related applications. A section is also devoted
to the physicochemical and biochemical properties of bioconjugates.
Finally, the book also provides a comprehensive
account on the significance of bioconjugation which is lacking
in many of the current available resources.
The book begins by providing an overview of the chemistry
involved in bioconjugation. Different types of bioconjugation
strategies available for the modification of
biomolecules (proteins, peptides, carbohydrates, polymers,
DNA) are presented. Classical bioconjugation approaches
are described first, followed by some recent bioconjugation
techniques. This section also provides detailed synthetic protocols
for some of the most important strategies for bioconjugation.

Polymer bioconjugates are then discussed separately in
three sections, namely polyethylene glycol (PEG), synthetic
polymer bioconjugates, and natural polymer bioconjugates.
PEG has been extensively used in the development of
macromolecular therapeutics and most of the current clinically
available therapeutics are PEGylated bioconjugates.
PEGylation has been used for proteins, anticancer drugs,
and other bioactive molecules such as peptides, antibodies,
oligonucleotides, aptamers, red blood cells, and more
recently, viruses. Conjugation of synthetic polymers to
biomolecules is an appealing strategy to produce new
biomacromolecules with distinctive properties. Typical
conjugation strategies are either “grafting from” or “grafting
to” approaches. In “grafting from” approach, monomerfunctionalized
biomolecules are polymerized to produce
synthetic polymer bioconjugates. On the other hand, in
“grafting to” approach, biomolecules are immobilized
by reactive coupling reactions. Random and site-specific
modifications of natural macromolecules have also been
extensively studied and, therefore, an elaborated section has
been devoted to this area.

The next section is focused on organic nanoparticle
bioconjugates. Different chemical strategies used to couple
biomolecules with liposomes, micelles, carbon nanotubes,
fullerene, and graphene are discussed. Bioconjugation
of biomolecules to those organic nanoparticles has
become increasingly important in drug formulation and therapeutic
delivery. Choosing the right chemistry between the
biomolecule and organic nanoparticle has been the focus of
great attention in recent years in view of improving the sustained
delivery of these bioconjugates to the targeted site
effectively. Carbon nanotubes, fullerene, and graphene have
unique properties and their coupling with biomolecules have
generated unique materials of high potency in biomedical
applications.

Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes

Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine.

With its emphasis on synthesis, properties and applications, this book enables readers to
understand the connection between chemistry and the biological application of bioconjugated materials.


2014 -- ISBN-10: 1118359143 -- 496 pages -- PDF -- 18 MB

Download


http://mediafire.com/download/02/003/Chemistry....plications.rar





المواضيع المشابهه
الموضوع كاتب الموضوع المنتدى مشاركات آخر مشاركة
Engineering Materials for Biomedical Applications سعد الدين كتب الهندسة الطبية الحيوية والبيولوجية 3 02-10-2014 04:21 PM
Piezoelectric Nanomaterials for Biomedical Applications سعد الدين كتب الهندسة الطبية الحيوية والبيولوجية 3 01-10-2014 11:35 PM
Practical Applications in Biomedical Engineering سعد الدين كتب الهندسة الطبية الحيوية والبيولوجية 4 30-09-2014 06:18 PM
Dendrimers in Biomedical Applications سعد الدين كتب الهندسة الطبية الحيوية والبيولوجية 4 30-09-2014 06:17 PM
Springer Biomedical Applications 2012 سعد الدين كتب الهندسة الطبية الحيوية والبيولوجية 3 27-09-2014 11:42 PM
05-10-2016, 10:47 AM
wissamrzaidan غير متصل
عضو جديد
رقم العضوية: 232854
تاريخ التسجيل: Feb 2009
المشاركات: 1
إعجاب: 0
تلقى 0 إعجاب على 0 مشاركة
تلقى دعوات الى: 0 موضوع
    #4  
شكرا لكم
جزاكم الله ما تستحقون
وانعم عليكم بما تتمنون من الخير لاهل الخير

24-10-2017, 02:05 PM
giverdi متصل
عضو مشارك
رقم العضوية: 960317
تاريخ التسجيل: Jun 2017
المشاركات: 30
إعجاب: 48
تلقى 0 إعجاب على 0 مشاركة
تلقى دعوات الى: 0 موضوع
    #5  
Thanks

 


Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications

English

Powered by vBulletin® Version
Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.
The owner and operator of the site is not responsible for the availability of, or any content provided.
Topics that are written in the site reflect the opinion of the author.
جميع ما يُطرح من مواضيع ومشاركات تعبر عن رأي كاتبها ولا تعبر عن رأي مالك الموقع أو الإدارة بأي حال من الأحوال.